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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RCC1
All Species:
22.12
Human Site:
T274
Identified Species:
40.56
UniProt:
P18754
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18754
NP_001041659.1
421
44969
T274
S
N
Y
H
Q
L
G
T
P
G
T
E
S
C
F
Chimpanzee
Pan troglodytes
XP_001152659
421
44920
T274
S
N
Y
H
Q
L
G
T
P
G
T
E
S
C
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544458
630
67681
T483
S
N
Y
H
Q
L
G
T
P
G
T
E
S
C
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE37
421
44912
T274
S
N
Y
H
Q
L
G
T
P
G
T
G
S
C
F
Rat
Rattus norvegicus
NP_001121661
421
45093
T274
S
N
Y
H
Q
L
G
T
P
G
T
G
S
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_427366
194
21051
S49
Q
E
R
V
V
Q
V
S
A
G
D
S
H
T
A
Frog
Xenopus laevis
P25183
424
45052
T279
S
N
Y
H
Q
L
G
T
K
N
T
Q
A
C
Y
Zebra Danio
Brachydanio rerio
Q6NYE2
495
54133
H337
G
G
Y
G
R
L
G
H
A
E
Q
K
D
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25171
547
58832
Q273
T
G
L
N
N
F
K
Q
L
A
H
E
T
K
G
Honey Bee
Apis mellifera
XP_394158
439
46956
L287
N
N
Y
Y
Q
I
G
L
K
D
P
V
T
H
F
Nematode Worm
Caenorhab. elegans
Q18211
569
61466
I403
N
N
Y
A
Q
L
G
I
K
V
D
E
A
D
V
Sea Urchin
Strong. purpuratus
XP_001191815
424
45249
L279
N
N
Y
H
H
L
G
L
E
N
V
K
S
W
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21827
482
52995
R323
A
L
V
T
K
P
K
R
L
A
L
P
D
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
64.7
N.A.
93.8
93.3
N.A.
N.A.
37
75.9
22.2
N.A.
29
45.5
29.5
52.8
Protein Similarity:
100
99.7
N.A.
65.8
N.A.
96.9
96.6
N.A.
N.A.
42
85.6
40
N.A.
43.6
63
42.5
70.7
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
6.6
66.6
20
N.A.
6.6
33.3
40
46.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
86.6
33.3
N.A.
26.6
60
53.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
16
16
0
0
16
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
16
0
16
8
0
% D
% Glu:
0
8
0
0
0
0
0
0
8
8
0
39
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
54
% F
% Gly:
8
16
0
8
0
0
77
0
0
47
0
16
0
0
8
% G
% His:
0
0
0
54
8
0
0
8
0
0
8
0
8
8
0
% H
% Ile:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
16
0
24
0
0
16
0
8
0
% K
% Leu:
0
8
8
0
0
70
0
16
16
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
24
70
0
8
8
0
0
0
0
16
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
8
0
0
39
0
8
8
0
0
0
% P
% Gln:
8
0
0
0
62
8
0
8
0
0
8
8
0
0
0
% Q
% Arg:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
47
0
0
0
0
0
0
8
0
0
0
8
47
0
0
% S
% Thr:
8
0
0
8
0
0
0
47
0
0
47
0
16
8
0
% T
% Val:
0
0
8
8
8
0
8
0
0
8
8
8
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
77
8
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _